RNA Details
Disease Name
diabetic nephropathy
Tissue
kidney
RNA Symbol
miR-17-5p
RNA ID
MIMAT0000070
RNA Type
miRNA
Alteration Pattern
up regulation
Species
homo sapiens
Detection Methods
RT-qRT-PCR;flow cytometry;western blot etc.
Target
KIF23
Pathway
WNT SIGNALING PATHWAY
PubMed ID
34014023
Title
MiR-17-5p downregulation alleviates apoptosis and fibrosis in high glucose-induced human mesangial cells through inactivation of Wnt/beta-catenin signaling by targeting KIF23
Year
2021
Function
MiR-17-5p inhibition alleviates the apoptosis and fibrosis in high glucose-treated HMCs by targeting KIF23 activating Wnt/beta-catenin signaling.